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The increased oxidative stress in the brain may be due to impairments in the bloodbrain barrier (BBB): one study found that ASD patients have lower levels of endothelial adhesion molecules, which suggest blockage of peripheral leukocytes into the central nervous system (Onore et al., 2012)

Recovery of hypoglycemia awareness in long-standing type 1 diabetes: a multicenter 2 2 factorial randomized controlled trial comparing insulin pump with multiple daily injections and continuous with conventional glucose self-monitoring (HypoCOMPaSS)

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