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Additionally, the AMPK activator AICAR (5-aminoimidazole-4-carboxamide ribonucleoside) (1 mM) was shown to upregulate AMPK expression in H9c2 cells exposed to high glucose and fat conditions ( Saikosaponin A (SSA) and Saikosaponin D (SSD) are triterpenoid saponins extracted from Bupleurum chinense DC., known for their anti-inflammatory, antipyretic, and hepatoprotective effects

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Sun P, Nie X, Chen X, Yin L, Luo J, Sun L, Wan C, Jiang S (2018) Nrf2 signaling elicits a neuroprotective role against PFOS-mediated oxidative damage and apoptosis

References An W, Dong X, Tan B, Yang Q, Chi S, Zhang S, Liu H, Yang Y (2021) Dietary n-3 long chain polyunsaturated fatty acids affect the serum biochemical parameters, lipid-metabolism-related of gene expression and intestinal health of juvenile hybrid grouper ( Epinephelus fuscoguttatus Epinephelus lanceolatu)