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With respect to cancer, the presence of a relatively high amount of transcript in biopsied tissue from an individual may indicate a predisposition for the development of the disease, or may provide a means for detecting the disease prior to the appearance of actual clinical symptoms

For example, the hydroxyl group in tyrosine increases its reactivity and solubility compared to phenylalanine

The way a person reacts to alcohol, including the likelihood of developing alcohol-related liver illness, can be affected by variations in the genes encoding important enzymes involved in the metabolism of ethanol

Methods: This is a prospective, investigator-initiated, proof-of-concept pilot study: Evaluating LIver Stiffness and steatosis as a TM in patients with AUD (ELISA)