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A study of 3D organotypic nasal epithelial culture showed that the impact of IQOS was substantially lower than CS in terms of cytotoxicity, tissue morphology, proinflammatory mediators, ciliary function, transcriptome perturbations, and miRNA expression profiles 59

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In fact, they deemed the evidence on the health benefits or risks of HTPs as inconclusive. Blowing smoke on HTPs The researchers dug into molecular changes in the body known as biomarkers to understand the potential impact of HTPs