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Combining them would require very careful dose escalation to avoid overwhelming GI effects." "If CagriSema (cagrilintide + semaglutide) works as well as trials suggest, adding glucagon activation from retatrutide could push results even further." These community insights, while valuable, should be considered preliminary observations rather than clinical evidence

While specific therapies for IBM are still lacking, NAD + boosters have shown promising results in various models, including nematodes with amyloid aggregation, aged rodents, and human muscle cells from IBM patients

Dimova S, Hoet PH, Dinsdale D, Nemery B

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